Fludarabine attenuates inflammation and dysregulated autophagy in alveolar macrophages via inhibition of STAT1/IRF1 pathway
The inhibition of STAT1/IRF1 by Fluda plays a pivotal role in modulating dysregulated autophagy by suppressing the MAPK and NF-κB p65 pathways in ALI.
Authors
- Jeong-Ran Park
- Hanbyeol Lee
- Sung‐Joon Cho (ORCID: https://orcid.org/0000-0002-3277-0259)
- Seung‐Jin Kim (ORCID: https://orcid.org/0000-0002-6062-1736)
- Woojin Kim (ORCID: https://orcid.org/0000-0001-5520-4228)
- Sungmin Park (ORCID: https://orcid.org/0000-0003-1162-4639)
- Joo-Yeon Lee (ORCID: https://orcid.org/0000-0003-4319-6341)
- Se‐Ran Yang (ORCID: https://orcid.org/0000-0002-2422-213X)
- Seok-Ho Hong
- Semin Ryu
- Oliver Eickelberg
Institutions
- Kangwon National University (KR)
- University of Pittsburgh (US)
Publication Details
- Journal
- Laboratory Animal Research
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1186/s42826-025-00245-7
- Citations
- 3
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- National Research Foundation
- Ministry of Environment
- National Research Foundation of Korea
- Ministry of Education, India
- Korea Environmental Industry and Technology Institute