IKZF1 as a potential therapeutic target for dendritic cell-mediated immunotherapy in IgA nephropathy
This study delineated key patterns of immune cell infiltration in IgAN and identified diagnostic biomarkers associated with DCs, offering valuable insights into the potential therapeutic targeting of IKZF1<sup>+</sup> DCs.
Authors
- Chunjia Sheng
- Chuyue Zhang (ORCID: https://orcid.org/0000-0001-8510-3831)
- Fei Peng (ORCID: https://orcid.org/0009-0009-7944-3878)
- Guangyan Cai (ORCID: https://orcid.org/0000-0001-8586-6353)
- Jie Wu (ORCID: https://orcid.org/0000-0002-8880-2520)
- Jikai Xia
- Yinghua Zhao (ORCID: https://orcid.org/0000-0003-2101-392X)
- Jiayi He (ORCID: https://orcid.org/0000-0003-4361-3379)
- Lingling Wu (ORCID: https://orcid.org/0000-0002-7166-3966)
- Xiangmei Chen (ORCID: https://orcid.org/0000-0001-8774-6021)
- Yilun Qu
- Shuwei Duan (ORCID: https://orcid.org/0000-0003-1306-5236)
- Yena Zhou
Institutions
- Nankai University (CN)
- Sichuan University (CN)
- Chinese PLA General Hospital (CN)
- Shantou University (CN)
- West China Hospital of Sichuan University (CN)
- First Affiliated Hospital of Shantou University Medical College (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-05-07
- DOI
- https://doi.org/10.1186/s12964-025-02196-x
- Citations
- 1
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- National Natural Science Foundation of China