Is programmed death-ligand 1 positivity a predictor of poor survival in patients with different histological subtypes of pancreatic cancer?
Our findings suggest that PD-L1 positivity is notably prevalent in signet ring cell carcinoma of the pancreas and is strongly associated with poor survival outcomes. Given these results, further studies with larger patient cohorts are warranted to validate these observations and explore potential therapeutic implications.
Authors
- Tevhide Bilgen Özcan (ORCID: https://orcid.org/0000-0002-8098-960X)
- Eren Altun (ORCID: https://orcid.org/0000-0001-9110-8364)
- Ceren Canbey Göret (ORCID: https://orcid.org/0000-0003-0564-4158)
- Esra Paşaoğlu (ORCID: https://orcid.org/0000-0001-8967-9061)
- Sena Şen (ORCID: https://orcid.org/0000-0003-3967-8903)
- Fikret Ezbercı (ORCID: https://orcid.org/0000-0003-3540-3822)
- Taha Yusuf Kuzan (ORCID: https://orcid.org/0000-0002-5420-8507)
- Senem Karabulut (ORCID: https://orcid.org/0000-0003-4740-9973)
Institutions
- University of Health Science (KH)
- Bağcılar Eğitim ve Araştırma Hastanesi (TR)
- Education Training And Research (US)
- Sağlık Bilimleri Üniversitesi (TR)
- Istanbul University (TR)
- University of Health Sciences Antigua (AG)
Publication Details
- Journal
- CytoJournal
- Published
- 2025-05-06
- DOI
- https://doi.org/10.25259/cytojournal_2_2025
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09