Prevalence of Carbapenem Resistant Enterobacteriaceae Isolates among Pregnant Women of Rural Areas from Dehradun, Uttarakhand, India

The aim of the study is to determine the prevalence and antimicrobial resistance patterns of carbapenem-resistant Enterobacteriaceae isolated from pregnant women in rural areas of Dehradun, Uttarakhand, India. During this study, 250 clinical samples were gathered 88 from the outpatient and 162 from the inpatients side. Along the way, researchers identified 110 gram-negative bacilli from the Enterobacteriaceae group using Gram’s stain, negative stain, and the standard biochemical tests. A phenotypic detection was done by the Modified Hodge test and Imp-EDTA disk synergy test. Interestingly, these findings generally match earlier work, which points out that specimen types - blood, sputum, pus, urine, or bronchoalveolar lavage—often show quite a bit of variability. In this sample set, the bacteria turned out to be 60 Escherichia coli, 29 Klebsiella pneumoniae, 13 Pseudomonas aeruginosa, and 8 Proteus mirabilis, underscoring a diverse picture of infections. The objective of the study is to determine the prevalence of Carbapenem Resistant Enterobacteriaceae among pregnant women in rural areas of Dehradun, Uttarakhand, India. Rural Dehradun presents unique conditions that justify focused research: limited healthcare infrastructure, high antibiotic misuse due to over-the-counter access, poor sanitation and lack of routine microbial screening during pregnancy. Overall, this spread highlights why keeping an ongoing, careful watch and making spot-on identifications is so important, both in outpatient and inpatient settings, to guide effective antimicrobial therapy.

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Publication Details

Journal
Asian Journal of Microbiology and Biotechnology
Published
2025-05-03
DOI
https://doi.org/10.56557/ajmab/2025/v10i19299
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
Field-Weighted Citation Impact
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article

Prevalence of Carbapenem Resistant Enterobacteriaceae Isolates among Pregnant Women of Rural Areas from Dehradun, Uttarakhand, India

Rajeev Gautam, Ashish Uniyal, Vishal Sawarn
Asian Journal of Microbiology and Biotechnology
Antibiotic Resistance in Bacteria
article

Prevalence of Carbapenem Resistant Enterobacteriaceae Isolates among Pregnant Women of Rural Areas from Dehradun, Uttarakhand, India

Rajeev Gautam, Ashish Uniyal, Vishal Sawarn
article en

Abstract

The aim of the study is to determine the prevalence and antimicrobial resistance patterns of carbapenem-resistant Enterobacteriaceae isolated from pregnant women in rural areas of Dehradun, Uttarakhand, India. During this study, 250 clinical samples were gathered 88 from the outpatient and 162 from the inpatients side. Along the way, researchers identified 110 gram-negative bacilli from the Enterobacteriaceae group using Gram’s stain, negative stain, and the standard biochemical tests. A phenotypic detection was done by the Modified Hodge test and Imp-EDTA disk synergy test. Interestingly, these findings generally match earlier work, which points out that specimen types - blood, sputum, pus, urine, or bronchoalveolar lavage—often show quite a bit of variability. In this sample set, the bacteria turned out to be 60 Escherichia coli, 29 Klebsiella pneumoniae, 13 Pseudomonas aeruginosa, and 8 Proteus mirabilis, underscoring a diverse picture of infections. The objective of the study is to determine the prevalence of Carbapenem Resistant Enterobacteriaceae among pregnant women in rural areas of Dehradun, Uttarakhand, India. Rural Dehradun presents unique conditions that justify focused research: limited healthcare infrastructure, high antibiotic misuse due to over-the-counter access, poor sanitation and lack of routine microbial screening during pregnancy. Overall, this spread highlights why keeping an ongoing, careful watch and making spot-on identifications is so important, both in outpatient and inpatient settings, to guide effective antimicrobial therapy.

Asian Journal of Microbiology and BiotechnologyVol. 10(1)
Doon University (IN)
Openalex Percentile: Top 93%
Antibiotic Resistance in Bacteria
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Prevalence of Carbapenem Resistant Enterobacteriaceae Isolates among Pregnant Women of Rural Areas from Dehradun, Uttarakhand, India — Rajeev Gautam, Ashish Uniyal, et al. · Asian Journal of Microbiology and Biotechnology (2025) | TGRS Research Map | TGRS