Myocardial fibrosis in primary aldosteronism
In patients with primary aldosteronism, focal replacement fibrosis was associated with cardiac afterload factors such as blood pressure, while diffuse interstitial fibrosis was associated with hyperaldosteronism. The amino-acid metabolism, especially the L-glutamate metabolism, might be involved in the process of myocardial fibrosis.
Authors
- Ji‐Guang Wang (ORCID: https://orcid.org/0000-0001-8511-1524)
- Xiaofei Ye (ORCID: https://orcid.org/0000-0003-3692-1285)
- Yan Li (ORCID: https://orcid.org/0000-0002-6857-9464)
- Yilin Chen (ORCID: https://orcid.org/0000-0001-8737-2824)
- Limin Zhu
- Chi‐Hua Chen (ORCID: https://orcid.org/0000-0002-3547-7584)
- Ting‐Yan Xu (ORCID: https://orcid.org/0009-0009-6318-308X)
- Jianzhong Xu (ORCID: https://orcid.org/0000-0002-9702-4900)
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Shanghai Institute of Hypertension (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-05-06
- DOI
- https://doi.org/10.3389/fendo.2025.1567876
- Citations
- 1
- Primary Topic
- Hormonal Regulation and Hypertension
- Type
- article
- Field-Weighted Citation Impact
- 1.29