Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis
Our findings indicate that CCL5, LOX, C3, and PLG are significantly associated with the progression and prognosis of ccRCC, highlighting their potential as prognostic biomarkers. These results provide a foundation for future research aimed at uncovering the underlying mechanisms and identifying potential therapeutic targets for ccRCC.
Authors
- Feng Cheng (ORCID: https://orcid.org/0000-0003-3619-8090)
- Mingyong Li (ORCID: https://orcid.org/0000-0002-8054-5697)
- Yude Hong
- Libo Chen (ORCID: https://orcid.org/0000-0003-2839-0920)
- Zhenwei Xie (ORCID: https://orcid.org/0000-0001-5996-390X)
- Weiming Deng (ORCID: https://orcid.org/0000-0003-4329-5059)
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-05-06
- DOI
- https://doi.org/10.3389/fmolb.2025.1587196
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00