Impact of polypharmacy phenogroups on different heart failure phenotypes in patients with chronic heart failure: a retrospective examination of real-world cohort

In patients with chronic Heart failure, guideline directed polypharmacy was associated with improved survival, particularly in HFpEF and HFmrEF phenotypes. However, non-heart failure-related polypharmacy is associated with worse outcomes including ICU admissions, necessitating need for targeted interventions for this group of patients.

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Journal
Frontiers in Pharmacology
Published
2025-05-06
DOI
https://doi.org/10.3389/fphar.2025.1526112
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Impact of polypharmacy phenogroups on different heart failure phenotypes in patients with chronic heart failure: a retrospective examination of real-world cohort

Ahmad Radaideh, Mohammed Danjuma, Ahmed Tarek Aboughalia, Abdul Haseeb Said Wali et al.
Frontiers in Pharmacology
Heart Failure Treatment and Management
article

Impact of polypharmacy phenogroups on different heart failure phenotypes in patients with chronic heart failure: a retrospective examination of real-world cohort

Ahmad Radaideh, Mohammed Danjuma, Ahmed Tarek Aboughalia, Abdul Haseeb Said Wali, Joud Abuodeh, Aseel Sukik, Abdel-Naser Y Elzouki, Oyelola A. Adegboye, Osama El‐Sayed, Mohammed Amer
article en

Abstract

In patients with chronic Heart failure, guideline directed polypharmacy was associated with improved survival, particularly in HFpEF and HFmrEF phenotypes. However, non-heart failure-related polypharmacy is associated with worse outcomes including ICU admissions, necessitating need for targeted interventions for this group of patients.

Frontiers in PharmacologyVol. 16
Charles Darwin University (AU), Menzies School of Health Research (AU), NHS Grampian (GB), Hamad General Hospital (QA), Dr Gray's Hospital (GB), Weill Cornell Medical College in Qatar (QA), Hamad Medical Corporation (QA), Qatar University (QA)
Qatar National Library
Openalex Percentile: Top 83%
Heart Failure Treatment and Management
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Impact of polypharmacy phenogroups on different heart failure phenotypes in patients with chronic heart failure: a retrospective examination of real-world cohort — Ahmad Radaideh, Mohammed Danjuma, et al. · Frontiers in Pharmacology (2025) | TGRS Research Map | TGRS