Transcriptomic and metabolomic analysis of the antibacterial mechanism of sanguinarine against Enterobacter cloacae in vitro

SAN exhibited potential antibacterial activity against E. cloacae, which can effectively inhibit its growth and disrupt its bacterial morphology and exert antibacterial effect through multiple pathways, and can be used as a potential substitute for antibiotics.

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Publication Details

Journal
BMC Microbiology
Published
2025-05-06
DOI
https://doi.org/10.1186/s12866-025-03992-8
Citations
9
Primary Topic
Berberine and alkaloids research
Type
article
Field-Weighted Citation Impact
12.55
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article

Transcriptomic and metabolomic analysis of the antibacterial mechanism of sanguinarine against Enterobacter cloacae in vitro

Jianguo Zeng, Haojie Sha, Dingding Su, Wen‐Lu Bi et al.
9 citations
BMC Microbiology
Berberine and alkaloids research
12.55
article

Transcriptomic and metabolomic analysis of the antibacterial mechanism of sanguinarine against Enterobacter cloacae in vitro

Jianguo Zeng, Haojie Sha, Dingding Su, Wen‐Lu Bi, Ting Yang
article en
9 citations

Abstract

SAN exhibited potential antibacterial activity against E. cloacae, which can effectively inhibit its growth and disrupt its bacterial morphology and exert antibacterial effect through multiple pathways, and can be used as a potential substitute for antibiotics.

BMC MicrobiologyVol. 25(1)
Hunan Agricultural University (CN), Weifang University (CN)
Zero hunger
Openalex Percentile: Top 1%
Berberine and alkaloids research
12.55
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