Neuron-specific enolase in patients with acute and chronic schizophrenia, diversity of approaches: marker of neuronal death, neurodegeneration or neurodevelopmental theory in schizophrenia? a single-center case-control study

The study found lower NSE levels in patients with schizophrenia. A tendency towards correlation between severity of negative symptoms of schizophrenia and decreased levels of NSE were observed. In addition, a trend was noted between an increase in NSE level and the severity of positive symptoms. The results of the experiment should be confirmed in further studies.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2025-05-06
DOI
https://doi.org/10.3389/fpsyt.2025.1520192
Primary Topic
S100 Proteins and Annexins
Type
article
Field-Weighted Citation Impact
0.00

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article

Neuron-specific enolase in patients with acute and chronic schizophrenia, diversity of approaches: marker of neuronal death, neurodegeneration or neurodevelopmental theory in schizophrenia? a single-center case-control study

Beata M. Labuz-Roszak, Alicja Sierakowska, Mateusz Łukasz Roszak, Ewa Niewiadomska et al.
Frontiers in Psychiatry
S100 Proteins and Annexins
article

Neuron-specific enolase in patients with acute and chronic schizophrenia, diversity of approaches: marker of neuronal death, neurodegeneration or neurodevelopmental theory in schizophrenia? a single-center case-control study

Beata M. Labuz-Roszak, Alicja Sierakowska, Mateusz Łukasz Roszak, Ewa Niewiadomska, Anna Bieniasiewicz, Sebastian Łabuda
article en

Abstract

The study found lower NSE levels in patients with schizophrenia. A tendency towards correlation between severity of negative symptoms of schizophrenia and decreased levels of NSE were observed. In addition, a trend was noted between an increase in NSE level and the severity of positive symptoms. The results of the experiment should be confirmed in further studies.

Frontiers in PsychiatryVol. 16
Medical University of Silesia (PL), University of Opole (PL), Children's Specialized Hospital (US)
Uniwersytet Opolski
Openalex Percentile: Top 91%
S100 Proteins and Annexins
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