Computational analysis of learning in young and ageing brains

Learning and memory are fundamental processes of the brain which are essential for acquiring and storing information. However, with ageing the brain undergoes significant changes leading to age-related cognitive decline. Although there are numerous studies on computational models and approaches which aim to mimic the learning process of the brain, they often concentrate on generic neural function exhibiting the potential need for models that address age-related changes in learning. In this paper, we present a computational analysis focusing on the differences in learning between young and old brains. Using a bipartite graph as an artificial neural network to model the synaptic connections, we simulate the learning processes of young and older brains by applying distinct biologically inspired synaptic weight update rules. Our results demonstrate the quicker learning ability of young brains compared to older ones, consistent with biological observations. Our model effectively mimics the fundamental mechanisms of the brain related to the speed of learning and reveals key insights on memory consolidation.

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Publication Details

Journal
Frontiers in Computational Neuroscience
Published
2025-05-06
DOI
https://doi.org/10.3389/fncom.2025.1565660
Primary Topic
Advanced Memory and Neural Computing
Type
article
Field-Weighted Citation Impact
0.00

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article

Computational analysis of learning in young and ageing brains

Amit Anand, Karl-Peter Giese, Jayani Hewavitharana, Kathleen Steinhofel et al.
Frontiers in Computational Neuroscience
Advanced Memory and Neural Computing
article

Computational analysis of learning in young and ageing brains

Amit Anand, Karl-Peter Giese, Jayani Hewavitharana, Kathleen Steinhofel, Carolina Moretti Ierardi
article en

Abstract

Learning and memory are fundamental processes of the brain which are essential for acquiring and storing information. However, with ageing the brain undergoes significant changes leading to age-related cognitive decline. Although there are numerous studies on computational models and approaches which aim to mimic the learning process of the brain, they often concentrate on generic neural function exhibiting the potential need for models that address age-related changes in learning. In this paper, we present a computational analysis focusing on the differences in learning between young and old brains. Using a bipartite graph as an artificial neural network to model the synaptic connections, we simulate the learning processes of young and older brains by applying distinct biologically inspired synaptic weight update rules. Our results demonstrate the quicker learning ability of young brains compared to older ones, consistent with biological observations. Our model effectively mimics the fundamental mechanisms of the brain related to the speed of learning and reveals key insights on memory consolidation.

Frontiers in Computational NeuroscienceVol. 19
King's College London (GB)
King's College London
Quality Education
Openalex Percentile: Top 92%
Advanced Memory and Neural Computing
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Computational analysis of learning in young and ageing brains — Amit Anand, Karl-Peter Giese, et al. · Frontiers in Computational Neuroscience (2025) | TGRS Research Map | TGRS