Outcome of In Vitro Fertilization (IVF) Treatment in Infertile Couples-ARetrospective Study

Background: In Vitro Fertilization (IVF) offers hope to many infertile couples globally, and understanding the factors associated with pregnancy outcome is crucial for medical professionals and aspiring parents. Aim of the study: The aim of this study was to assess the outcome of IVF treatment in infertile couples. Methods: This retrospective study was conducted in Department of Obstetrics and Gynaecology, Nova IVF Fertility Bangladesh, Dhaka, Bangladesh, during the period from February 2022 to January 2024. Total 320 infertile couple were included in this study. Result: The mean age was 32.4 years (SD±5.6 years). The majority (56.9%) experienced infertility for 1 to 4 years (SD±4.6 years). The causes of infertility varied, with 17.8% due to male factors, 36.3% to female factors, 6.3% combined, and 39.7% unexplained. Most subjects (69.7%) underwent standard IVF, with 33.8% achieving successful pregnancies and 6.9% resulting in live births. Women aged 25-29 and 30-34 had higher success rates. A significant correlation was found between the duration of infertility and successful pregnancy rates, particularly for those experiencing infertility for 4 to 9 years. Male and female infertility factors significantly influenced pregnancy outcomes. AMH levels showed a significant correlation with pregnancy outcomes, with normal AMH levels being more favorable for successful pregnancy and live birth outcomes. Conclusion: The study finds higher IVF success in the 25-29 and 30-34 age groups, with shorter infertility durations. Male and female infertility factors significantly impact outcomes, and normal Anti-Müllerian Hormone (AMH) levels are linked to better pregnancy results.