Microscopy with microfluidics in microgravity using FlightScope

With planned missions to the moon and Mars, it has never been more important to study the impact of microgravity on biological organisms. Parabolic flights are one of the most accessible microgravity research platforms but present challenges: short periods of microgravity and aircraft vibration. Live-imaging is necessary to readout any real-time phenotypes so we developed FlightScope, a new microscopy and microfluidics platform to study dynamic cellular processes in microgravity.

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Publication Details

Journal
npj Microgravity
Published
2025-05-06
DOI
https://doi.org/10.1038/s41526-025-00470-3
Citations
2
Primary Topic
Spaceflight effects on biology
Type
article
Field-Weighted Citation Impact
2.33

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article

Microscopy with microfluidics in microgravity using FlightScope

Alexander Stokes, Jack Dawson, Manu Prakash, Adam J. M. Wollman et al.
2 citations
npj Microgravity
Spaceflight effects on biology
2.33
article

Microscopy with microfluidics in microgravity using FlightScope

Alexander Stokes, Jack Dawson, Manu Prakash, Adam J. M. Wollman, Yusuf Furkan Ugurluoglu, Katrina E Crompton, Thomas Wareing, Hongquan Li, Connor Richardson, Koren Murphy
article en
2 citations

Abstract

With planned missions to the moon and Mars, it has never been more important to study the impact of microgravity on biological organisms. Parabolic flights are one of the most accessible microgravity research platforms but present challenges: short periods of microgravity and aircraft vibration. Live-imaging is necessary to readout any real-time phenotypes so we developed FlightScope, a new microscopy and microfluidics platform to study dynamic cellular processes in microgravity.

npj MicrogravityVol. 11(1)
Newcastle University (GB), Stanford University (US)
Wellcome, Wellcome Trust, UK Space Agency, European Space Agency, Academy of Medical Sciences, Newcastle University
Openalex Percentile: Top 13%
Spaceflight effects on biology
2.33
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Microscopy with microfluidics in microgravity using FlightScope — Alexander Stokes, Jack Dawson, et al. · npj Microgravity (2025) | TGRS Research Map | TGRS