Global Trends and Hotspots in Dulaglutide in the Fields of Diabetes, Obesity, and Cardiovascular Research: A Bibliometric Analysis

Aims: Dulaglutide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has captured significant attention in the fields of diabetes, obesity, and cardiovascular research. This scientometric analysis was to identify global trends and hotspots in Dulaglutide research (DGR). Methods: A comprehensive search of the Scopus database was conducted to retrieve Englishlanguage data-driven studies published from the inception of the DGR from 2010 to December 2023. The collected data were subsequently analyzed using VOSviewer and Bibliometrix software. This study sheds light on the intellectual structure of the DGR, which includes identifying key research areas, influential authors, and collaborations, as well as the conceptual structure comprising the identified themes and trends within DGR. Results: The study identified a significant growth in DGR, with the United States, China, and the United Kingdom leading in research output. Canada exhibited strong international collaboration. A small group of highly productive authors contributed disproportionately to the literature, consistent with Lotka’s law. Research trends have evolved from broad themes in cardiovascular health to more specialized studies focusing on the drug’s mechanisms, comparative effectiveness, and emerging applications, such as non-alcoholic fatty liver disease. Citation analysis revealed cardiovascular outcomes, real-world effectiveness, and GLP-1 receptor interactions are among the most researched areas. Conclusion: DGR is a rapidly expanding field with shifting priorities from general diabetes management to specific pharmacological and clinical outcomes. The findings underscore the need for more diverse geographic representation in research and highlight knowledge gaps that future studies should address. This bibliometric analysis provides valuable insights into the intellectual landscape of Dulaglutide research, aiding future investigations and clinical applications.