A Comparison of Monotherapy and Combination Therapy With Antipsychotic Medications for Intensive Care Unit Delirium: A Retrospective Cohort Study

In patients with ICU delirium, there was no difference in duration of delirium among patients receiving monotherapy compared with combination therapy with antipsychotics, though they may be sicker and have a higher mortality. Patients commonly remain on antipsychotics at hospital discharge, the implications of which warrant further study.

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Publication Details

Journal
Annals of Pharmacotherapy
Published
2025-05-06
DOI
https://doi.org/10.1177/10600280251322199
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

A Comparison of Monotherapy and Combination Therapy With Antipsychotic Medications for Intensive Care Unit Delirium: A Retrospective Cohort Study

Anh Do Nguyen, Timothy Allison-Aipa, Paul Albini, Justin Chang
Annals of Pharmacotherapy
Intensive Care Unit Cognitive Disorders
article

A Comparison of Monotherapy and Combination Therapy With Antipsychotic Medications for Intensive Care Unit Delirium: A Retrospective Cohort Study

Anh Do Nguyen, Timothy Allison-Aipa, Paul Albini, Justin Chang
article en

Abstract

In patients with ICU delirium, there was no difference in duration of delirium among patients receiving monotherapy compared with combination therapy with antipsychotics, though they may be sicker and have a higher mortality. Patients commonly remain on antipsychotics at hospital discharge, the implications of which warrant further study.

Annals of PharmacotherapyVol. 60(1)
Riverside University Health System - Medical Center (US)
Good health and well-being
Openalex Percentile: Top 88%
Intensive Care Unit Cognitive Disorders
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