Cannabigerol and Cannabinoid Receptors in Major Depressive Disorder: Network Pharmacology, Molecular Docking, and In-vivo Analysis
Cannabigerol has shown significant depressive alleviating potential in mice exposed to chronic and unpredictable stress regimes, possibly via interaction with cannabinoid receptors as indicated by <i>in-silico</i> modelling, which has been validated by our findings of the <i>in-vivo</i> protocol.
Authors
- Rubina Bhutani (ORCID: https://orcid.org/0000-0002-1115-6436)
- Saud O. Alshammari (ORCID: https://orcid.org/0000-0002-6251-3149)
- Abdulkarim Alshammari (ORCID: https://orcid.org/0009-0008-6318-4341)
- Md Azhar Iqbal (ORCID: https://orcid.org/0009-0002-4527-5676)
- Abhishek Sharma (ORCID: https://orcid.org/0000-0001-7859-867X)
- S.K. Sharma (ORCID: https://orcid.org/0000-0001-8081-241X)
- Rahul Pratap Singh (ORCID: https://orcid.org/0000-0001-6807-0484)
- Qamar A. Alshammari (ORCID: https://orcid.org/0009-0005-5522-2916)
- Rohit Dutt (ORCID: https://orcid.org/0000-0001-6794-5533)
- Neha Rana (ORCID: https://orcid.org/0000-0002-8390-9898)
- Saahil Arora (ORCID: https://orcid.org/0000-0003-2278-1824)
Institutions
- Northern Border University (SA)
- Amity University (IN)
- Jamia Hamdard (IN)
- GD Goenka University (IN)
- Indira Gandhi National Tribal University (IN)
- Shree Guru Gobind Singh Tricentenary University (IN)
- Noida International University (IN)
- Gurugram University (IN)
Publication Details
- Journal
- Current Drug Discovery Technologies
- Published
- 2025-05-06
- DOI
- https://doi.org/10.2174/0115701638363093250324035540
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00