Effects of Cholinesterase Inhibitor Medication on QTc Interval in Memory Clinic Patients

We found no statistically significant association between ChEI use and QTc interval prolongation or an increased proportion of pathological QTc values during ChEI treatment. Larger studies are warranted to establish evidence-based recommendations on ECG monitoring during ChEI medication.

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Publication Details

Journal
Annals of Pharmacotherapy
Published
2025-05-06
DOI
https://doi.org/10.1177/10600280251328530
Primary Topic
Cardiac electrophysiology and arrhythmias
Type
article
Field-Weighted Citation Impact
0.00

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article

Effects of Cholinesterase Inhibitor Medication on QTc Interval in Memory Clinic Patients

Ville L. Langén, Maria Nuotio, H. Isotalo, Laura L. Ekblad et al.
1 links
Annals of Pharmacotherapy
Cardiac electrophysiology and arrhythmias
article

Effects of Cholinesterase Inhibitor Medication on QTc Interval in Memory Clinic Patients

Ville L. Langén, Maria Nuotio, H. Isotalo, Laura L. Ekblad, Joanna Karoliina Lehtovaara
article en

Abstract

We found no statistically significant association between ChEI use and QTc interval prolongation or an increased proportion of pathological QTc values during ChEI treatment. Larger studies are warranted to establish evidence-based recommendations on ECG monitoring during ChEI medication.

Annals of PharmacotherapyVol. 60(1)
University of Turku (FI), Turku University Hospital (FI), Turku PET Centre (FI), Varsinais-Suomen Sairaanhoitopiiri (FI)
Suomen Lääketieteen Säätiö
Good health and well-being
Openalex Percentile: Top 83%
Cardiac electrophysiology and arrhythmias
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