Unveiling the Prognostic Role of Synaptophysin in Conventional Colorectal Carcinomas
Among conventional CRCs, we provided evidence that Syn expression is associated with worse OS and DFS and contributes to predicting clinical outcome. Future studies should explore the molecular mechanisms underlying the acquisition of the neuroendocrine phenotype to identify new targeted treatment strategies.
Authors
- Silvia Uccella (ORCID: https://orcid.org/0000-0002-5714-7295)
- Filiberto Belli (ORCID: https://orcid.org/0000-0003-3973-4979)
- Massimo Milione (ORCID: https://orcid.org/0000-0002-1202-139X)
- Donata Galbiati
- Luca Agnelli (ORCID: https://orcid.org/0000-0003-0582-6170)
- Valentina Angerilli (ORCID: https://orcid.org/0000-0002-9799-9257)
- Andrea Vingiani (ORCID: https://orcid.org/0000-0002-9827-3976)
- Stefano La Rosa (ORCID: https://orcid.org/0000-0003-1941-2403)
- Vincenzo Lagano (ORCID: https://orcid.org/0000-0002-5965-0361)
- Giovanna Garzone
- Sara Pusceddu (ORCID: https://orcid.org/0000-0002-5096-660X)
- Matteo Fassan (ORCID: https://orcid.org/0000-0001-6515-5482)
- Giovanna Sabella (ORCID: https://orcid.org/0000-0002-1673-424X)
- Andrea Scardino (ORCID: https://orcid.org/0000-0001-7402-9197)
- Giovanni Centonze (ORCID: https://orcid.org/0000-0003-2864-7941)
- Giancarlo Pruneri (ORCID: https://orcid.org/0000-0002-7963-7172)
- Carlotta Pardo
- Alessandro Mangogna (ORCID: https://orcid.org/0000-0001-7910-1274)
- Carlo Capella
- Fausto Sessa
- Stefania Gobba
Institutions
- University of Insubria (IT)
- University of Udine (IT)
- Humanitas University (IT)
- University of Padua (IT)
- University of Trieste (IT)
- Istituto Oncologico Veneto (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Fondazione IRCCS Istituto Nazionale dei Tumori (IT)
- IRCCS Humanitas Research Hospital (IT)
- Aziende Socio Sanitarie Territoriale dei Sette Laghi
Publication Details
- Journal
- Neuroendocrinology
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1159/000545979
- Citations
- 4
- Primary Topic
- Neuroblastoma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.56
Funders
- Ministero della Salute