Icaritin Attenuates HSC Activation by Down-regulating the HIF-1αand TGF-β/Smad Signaling Pathways to Ameliorate Liver Fibrosis
Icaritin attenuated experimental liver fibrosis through the inhibition of the TGF-β/Smad and HIF-1α signaling pathways, highlighting its therapeutic potential for fibrotic liver diseases.
Authors
- Yaping Zhao (ORCID: https://orcid.org/0000-0002-3482-0942)
- Ke Du (ORCID: https://orcid.org/0009-0003-7240-2770)
- Na Huang (ORCID: https://orcid.org/0000-0001-7961-0677)
- Minghao Yin (ORCID: https://orcid.org/0000-0002-6226-2394)
- Keping Feng
- Chengbo Zhang (ORCID: https://orcid.org/0000-0003-2611-9627)
- Qiaoman Fei
- Yudan Fan
- Pengfei Liu (ORCID: https://orcid.org/0000-0002-4177-709X)
- Zongfang Li
Institutions
- Shanxi Medical University (CN)
- Second Affiliated Hospital of Xi'an Jiaotong University (CN)
- Shanxi Provincial People’s Hospital (CN)
Publication Details
- Journal
- Current Medicinal Chemistry
- Published
- 2025-05-05
- DOI
- https://doi.org/10.2174/0109298673362768250417052953
- Citations
- 1
- Primary Topic
- Medicinal Plant Pharmacodynamics Research
- Type
- article
- Field-Weighted Citation Impact
- 1.56