Epidermal growth factor receptor antibody and axial elongation in experimental myopia
Intravitreally administered panitumumab in young guinea pigs with LIM resulted in a dose-dependent and treatment frequency-dependent reduction in axial elongation, supporting the role of EGFR signalling in axial elongation.
Authors
- Ru‐Heng Zhang
- Yongan Andrew Yang (ORCID: https://orcid.org/0000-0003-1451-2923)
- Heyan Li (ORCID: https://orcid.org/0009-0002-6558-4724)
- Zhihua Zheng (ORCID: https://orcid.org/0000-0003-1025-5384)
- Wen‐Da Zhou
- Li Dong (ORCID: https://orcid.org/0000-0003-0120-5756)
- Xu‐Han Shi
- Chuyao Yu
- Hanqing Zhao (ORCID: https://orcid.org/0000-0003-0327-3699)
- Jost Bruno Jonas (ORCID: https://orcid.org/0000-0003-2972-5227)
- Hao‐Tian Wu (ORCID: https://orcid.org/0000-0001-6462-7193)
- Shanshan Wang (ORCID: https://orcid.org/0000-0001-7364-768X)
- Wenbin Wei (ORCID: https://orcid.org/0000-0003-2386-0989)
- Jiao‐Yue Dong (ORCID: https://orcid.org/0000-0002-8002-9086)
Institutions
- Beijing Tongren Hospital (CN)
- Capital Medical University (CN)
- Singapore National Eye Center (SG)
- L V Prasad Eye Institute (IN)
- Singapore Eye Research Institute (SG)
- Fondation de Rothschild (FR)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Ministry of Industry and Information Technology (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Acta Ophthalmologica
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1111/aos.17516
- Primary Topic
- Ocular Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Capital Medical University
- Sanming Project of Medicine in Shenzhen