Adapting OptCouple to Identify Strategies with Increased Product Yields in Community Cohorts of E. coli
Microbesas chemical factories provide an alternative sustainable approach for producing platform chemicals. Until recently, most efforts have involved engineering heterologous pathways into a single microbial chassis to maximise its production of a target chemical. More recently, cohorts of microbes have been used to engineer microbial communities to achieve higher yields than achieved in a single chassis.
Authors
- Jamie Twycross (ORCID: https://orcid.org/0000-0002-1684-0886)
- Nicole Pearcy (ORCID: https://orcid.org/0000-0001-8872-6436)
Institutions
- Engineering and Physical Sciences Research Council (GB)
- University of Nottingham (GB)
- Biotechnology and Biological Sciences Research Council (GB)
Publication Details
- Journal
- Metabolites
- Published
- 2025-05-06
- DOI
- https://doi.org/10.3390/metabo15050309
- Primary Topic
- Microbial Metabolic Engineering and Bioproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Directorate for Biological Sciences
- Biotechnology and Biological Sciences Research Council