Ergotamine/Caffeine Overdose in a Female Suffering From Migraine Headache: A Case Report

From Migraine Headache: A Case ReportBackground: Ergotamine is a very common antimigraine and is widely used in the management of headaches such as cluster and acute migraines.However, Ergotamine poisoning is an infrequent condition, and there are very few cases reported.Tachycardia and arterial spasms occasionally occur because of accidental overdosing or interactions.There are no specific antidotes, and none of the current treatments have proven efficacy.Case Report: Here, we describe a young female who intentionally consumed approximately 20 mg of ergotamine and experienced vomiting, vasospasm, and tachycardia.Fortunately, her symptoms improved with the administration of conservation therapy, enoxaparin, nifedipine, and methylprednisolone. Conclusion:Clinicians should be aware of the potential risk of vasoconstriction associated with ergotamine/caffeine toxicity and closely monitor patients for these side effects.

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Publication Details

Journal
Pharmaceutical and Biomedical Research
Published
2025-03-01
DOI
https://doi.org/10.32598/pbr.11.1.1301.1
Citations
1
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
1.47
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article

Ergotamine/Caffeine Overdose in a Female Suffering From Migraine Headache: A Case Report

Navid Khosravi, Amir Hasan Farzaneh
1 citations
Pharmaceutical and Biomedical Research
Migraine and Headache Studies
1.47
article

Ergotamine/Caffeine Overdose in a Female Suffering From Migraine Headache: A Case Report

Navid Khosravi, Amir Hasan Farzaneh
article en
1 citations

Abstract

From Migraine Headache: A Case ReportBackground: Ergotamine is a very common antimigraine and is widely used in the management of headaches such as cluster and acute migraines.However, Ergotamine poisoning is an infrequent condition, and there are very few cases reported.Tachycardia and arterial spasms occasionally occur because of accidental overdosing or interactions.There are no specific antidotes, and none of the current treatments have proven efficacy.Case Report: Here, we describe a young female who intentionally consumed approximately 20 mg of ergotamine and experienced vomiting, vasospasm, and tachycardia.Fortunately, her symptoms improved with the administration of conservation therapy, enoxaparin, nifedipine, and methylprednisolone. Conclusion:Clinicians should be aware of the potential risk of vasoconstriction associated with ergotamine/caffeine toxicity and closely monitor patients for these side effects.

Pharmaceutical and Biomedical ResearchVol. 11(1)
Mazandaran University of Medical Sciences (IR)
Gender equality
Openalex Percentile: Top 20%
Migraine and Headache Studies
1.47
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Ergotamine/Caffeine Overdose in a Female Suffering From Migraine Headache: A Case Report — Navid Khosravi, Amir Hasan Farzaneh · Pharmaceutical and Biomedical Research (2025) | TGRS Research Map | TGRS