Relationship between RT-PCR Threshold Cycle Values and Thorax CT Severity Score in COVID-19 Patients

Purpose: In this study, we aimed to investigate the relationship between RT-PCR Cycles Threshold (Ct) values, which provide information about the viral load, and CT severity score (CTSS), which is used to demonstrate lung involvement. Materials and Methods: Between January 1, 2021 and November 30, 2021, a total of 162 patients with lung auscultation findings and/or suspicious findings on posteroanterior chest radiography, along with a positive RT-PCR test, were included in the study. Viral loads, lung involvement, and mortality rates of the cases were analyzed based on the units in which they were hospitalized. Additionally, we investigated the correlation between comorbid diseases associated with COVID-19, CTSS (CT severity score), RT-PCR Ct viral load values, and age. Results: The CTSS showed a positive and significant correlation with age (p=0.017). Statistical analysis revealed no significant correlation between viral load and thoracic involvement (p=0.663). Conclusion: According to the present study, no significant correlation was found between RT-PCR Ct values, which play a crucial role in the diagnosis of COVID-19, and thoracic CT involvement. However, the prevalence of lung involvement and the mortality rate of the cases increased with age. Additionally, a significant correlation was observed between the CT severity score (CT-SS) and age. These findings pave the way for future in-depth research in this field, fostering a better understanding of the subject matter.