Urapidil as a neuroprotective agent: targeting hypoxia, inflammation, and oxidative stress in traumatic brain injury
Ura shows promising tissue-protective effects in TBI by targeting inflammation, oxidative stress, and apoptosis. This study provides a new perspective on the need for further development of Ura for therapeutic use.
Authors
- Muhammet Yusuf Tepebaşı (ORCID: https://orcid.org/0000-0002-1087-4874)
- Mehmet Abdulkadir Sevük (ORCID: https://orcid.org/0000-0003-3875-9365)
- Halil Aşçı (ORCID: https://orcid.org/0000-0002-1545-035X)
- Pınar Karabacak (ORCID: https://orcid.org/0000-0002-6210-5962)
- İlter İlhan (ORCID: https://orcid.org/0000-0003-3739-9580)
- Orhan Berk İmeci (ORCID: https://orcid.org/0000-0002-3850-0137)
- Bekir Yıldırım (ORCID: https://orcid.org/0000-0003-2378-7697)
- Özlem Özmen (ORCID: https://orcid.org/0000-0002-5392-1626)
- Ahmet Bi̇ndal (ORCID: https://orcid.org/0000-0002-1971-6856)
Institutions
- Süleyman Demirel Üniversitesi (TR)
- Suleyman Demirel University (KZ)
- Burdur Mehmet Akif Ersoy Üniversitesi (TR)
Publication Details
- Journal
- European Journal of Trauma and Emergency Surgery
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1007/s00068-025-02873-z
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 0.00