Comparative evaluation of transforming growth factor-beta 1 release from dentin matrix with double antibiotic paste, probiotics, and simvastatin as intracanal medicaments: An in vitro study

A statistically significant difference in TGF-β1 release was observed among the three test groups. Simvastatin and probiotics can effectively be used as an ICM in regenerative endodontics due to their potential to release high amounts of TGF-β1 from the dentin matrix.

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Publication Details

Journal
Journal of Conservative Dentistry and Endodontics
Published
2025-05-01
DOI
https://doi.org/10.4103/jcde.jcde_131_25
Citations
2
Primary Topic
Endodontics and Root Canal Treatments
Type
article
Field-Weighted Citation Impact
3.58
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article

Comparative evaluation of transforming growth factor-beta 1 release from dentin matrix with double antibiotic paste, probiotics, and simvastatin as intracanal medicaments: An in vitro study

Duvvuri Lakshmi Malini, G. Prasanthi, Vishakha Agarwal, K. Hanisha Reddy et al.
2 citations
Journal of Conservative Dentistry and Endodontics
Endodontics and Root Canal Treatments
3.58
article

Comparative evaluation of transforming growth factor-beta 1 release from dentin matrix with double antibiotic paste, probiotics, and simvastatin as intracanal medicaments: An in vitro study

Duvvuri Lakshmi Malini, G. Prasanthi, Vishakha Agarwal, K. Hanisha Reddy, T. Murali Mohan, B. Devipriya
article en
2 citations

Abstract

A statistically significant difference in TGF-β1 release was observed among the three test groups. Simvastatin and probiotics can effectively be used as an ICM in regenerative endodontics due to their potential to release high amounts of TGF-β1 from the dentin matrix.

Journal of Conservative Dentistry and EndodonticsVol. 28(5)
Government Dental College and Hospital (IN)
Openalex Percentile: Top 9%
Endodontics and Root Canal Treatments
3.58
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