Biomechanical parameters quantified by MR elastography for predicting response to neoadjuvant chemotherapy and disease-free survival in breast cancer: a prospective longitudinal study
During NAC, patients with higher tumor stiffness and viscosity are less likely to achieve DFS and pCR. The biomechanical parameters exhibit excellent biological interpretability and serve as valuable biomarkers for predicting pCR and DFS in patients with breast cancer.
Authors
- Ting Yin (ORCID: https://orcid.org/0000-0003-2528-1630)
- Jiuquan Zhang (ORCID: https://orcid.org/0000-0003-0239-6988)
- Jinfang Shi
- Lingling Wang (ORCID: https://orcid.org/0000-0003-0272-2974)
- Lu Wang (ORCID: https://orcid.org/0000-0002-3134-2519)
- Lan Li (ORCID: https://orcid.org/0000-0002-0038-1953)
- Huifang Chen (ORCID: https://orcid.org/0000-0003-2016-1082)
- Ying Cao (ORCID: https://orcid.org/0000-0002-7787-1694)
- Yao Huang (ORCID: https://orcid.org/0000-0002-0866-1562)
- Sun Tang (ORCID: https://orcid.org/0000-0003-0143-5754)
- Haiping Huang (ORCID: https://orcid.org/0009-0003-5383-1721)
- Xueqin Gong (ORCID: https://orcid.org/0000-0001-8389-8765)
Institutions
- Chongqing University (CN)
- Chongqing Cancer Hospital (CN)
- Siemens (China) (CN)
Publication Details
- Journal
- Breast Cancer Research
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1186/s13058-025-02035-4
- Primary Topic
- Ultrasound Imaging and Elastography
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Chongqing University
- Natural Science Foundation of Chongqing
- Centre Scientifique et Technique du Bâtiment
- Fundamental Research Funds for the Central Universities
- Fundamental Research Funds for Central Universities of the Central South University