Mortality and exacerbations in bronchiectasis patients with carbapenem-resistant Pseudomonas aeruginosa isolation: a long-term retrospective cohort study
CRPA isolation was significantly associated with an increasing risk of acute exacerbations, overall and cause-specific mortality. These findings underscored the urgent need to strengthen antibiotic stewardship to reduce the emergence of CRPA and to implement early detection and targeted management strategies to improve outcomes for patients with CRPA.
Authors
- Qingqing Jia
- Weiming Lv (ORCID: https://orcid.org/0000-0001-9014-7732)
- Tong Xiang (ORCID: https://orcid.org/0000-0002-5286-587X)
- Jie Sun (ORCID: https://orcid.org/0000-0002-0702-9880)
- Hong Fan (ORCID: https://orcid.org/0000-0003-3389-6213)
- Dongguang Wang (ORCID: https://orcid.org/0000-0003-4344-4093)
- J. H. Chen (ORCID: https://orcid.org/0009-0005-9162-1500)
- Yongjiang Tang
- Lian Wang (ORCID: https://orcid.org/0000-0002-8793-7335)
- Shijie Zhang (ORCID: https://orcid.org/0000-0002-8041-0581)
- Sitong Liu (ORCID: https://orcid.org/0000-0001-7355-1549)
- Xiaoting Chen (ORCID: https://orcid.org/0000-0002-5606-3081)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Annals of Clinical Microbiology and Antimicrobials
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1186/s12941-025-00798-4
- Citations
- 2
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Sichuan University
- West China Hospital, Sichuan University