Comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on cardiovascular outcomes in older adults with type 2 diabetes mellitus: a target trial emulation study
Among older patients with T2DM, the initiation of ACEIs was associated with a trend toward lower risk of MACE compared to ARBs, implying the potential cardiovascular benefits of ACEIs in this population.
Authors
- Weihong Zeng (ORCID: https://orcid.org/0000-0003-3853-3630)
- Xiaodong Guan (ORCID: https://orcid.org/0000-0002-1290-3827)
- Na He (ORCID: https://orcid.org/0000-0002-9712-7782)
- Hongbo Lin (ORCID: https://orcid.org/0000-0002-9953-4752)
- Yang Xu (ORCID: https://orcid.org/0000-0002-1074-608X)
- Tiansheng Wang
- Peng Shen (ORCID: https://orcid.org/0000-0002-0176-127X)
- Til Stürmer
Institutions
- University of North Carolina at Chapel Hill (US)
- Peking University (CN)
- Ningbo Center for Disease Control and Prevention (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- Cardiovascular Diabetology
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1186/s12933-025-02753-1
- Citations
- 8
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 11.11
Funders
- American Diabetes Association
- National Natural Science Foundation of China
- Ministry of Science and Technology of the People's Republic of China
- Young Scientists Fund