Targeting α7 Nicotinic Acetylcholine Receptor for Modulating the Neuroinflammation of Dry Eye Disease Via Macrophages
Our findings underscore the activation of α7nAChR as a pioneering therapeutic approach for preserving corneal nerves balance and controlling inflammation in DED.
Authors
- Jiaxu Hong
- Kan Yang (ORCID: https://orcid.org/0000-0003-1563-1406)
- Yuqing Wu (ORCID: https://orcid.org/0000-0003-4883-5982)
- Xujiao Zhou (ORCID: https://orcid.org/0000-0002-9719-4889)
- Binbin Chu (ORCID: https://orcid.org/0000-0003-3275-9313)
- Yao He
- Yirou Zhang
Institutions
- Macau University of Science and Technology (MO)
- Fudan University (CN)
- Soochow University (CN)
- Shanghai Eye Disease Prevention & Treatment Center (CN)
- Eye & ENT Hospital of Fudan University (CN)
- First Hospital of Lanzhou University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1167/iovs.66.5.13
- Citations
- 7
- Primary Topic
- Nicotinic Acetylcholine Receptors Study
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- National Natural Science Foundation of China
- Fudan University
- Shanghai Municipal Education Commission
- Natural Science Foundation of Gansu Province
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Collaborative Innovation Center of Suzhou Nano Science and Technology
- Higher Education Discipline Innovation Project
- National Key Research and Development Program of China
- National Science Fund for Distinguished Young Scholars