MDMX enhances radiosensitivity in lung adenocarcinoma and squamous cell carcinoma by inhibiting P53-mediated autophagy
MDMX enhances LUAD and LUSC radiosensitivity by downregulating P53-mediated autophagy. High MDMX expression correlated with better clinical outcomes, suggesting that MDMX could be a potential biomarker for predicting radiotherapy response and prognosis in LUAD and LUSC patients.
Authors
- Ling Shao (ORCID: https://orcid.org/0000-0002-0285-9287)
- Nan-Nan Ji
- Yue‐Can Zeng (ORCID: https://orcid.org/0000-0002-0053-7540)
- Qing Li (ORCID: https://orcid.org/0000-0002-7930-2145)
- Jun-Nv Xu
- Shuning Li (ORCID: https://orcid.org/0000-0002-6233-5549)
Institutions
- Hainan Medical University (CN)
Publication Details
- Journal
- Cellular Oncology
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1007/s13402-025-01065-6
- Citations
- 2
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- National Natural Science Foundation of China
- Hainan Medical University
- Hainan Provincial Department of Science and Technology
- Education Department of Hainan Province