Individual-level cortical morphological network analysis in idiopathic normal pressure hydrocephalus: diagnostic and prognostic insights
The MIND-based morphological similarity network reveals coordinated cortical morphological alterations in iNPH and highlights its heterogeneity compared to AD. These findings offer potential biomarkers to differentiate iNPH from AD. Furthermore, the predictive efficacy of MIND-based features for postoperative outcomes underscores their utility as non-invasive preoperative tools for evaluating shunt surgery effectiveness.
Authors
- Guangwu Lin (ORCID: https://orcid.org/0000-0001-5085-2111)
- Shihong Li (ORCID: https://orcid.org/0000-0002-2204-7593)
- Xuhao Fang (ORCID: https://orcid.org/0000-0002-3733-3568)
- Xiao Liu (ORCID: https://orcid.org/0000-0002-5363-6331)
- L. Sun (ORCID: https://orcid.org/0000-0002-0034-2567)
- Yifeng Yang (ORCID: https://orcid.org/0000-0003-3072-159X)
- Meijing Yan
Institutions
- Fudan University (CN)
- Huadong Hospital (CN)
Publication Details
- Journal
- Fluids and Barriers of the CNS
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1186/s12987-025-00653-w
- Citations
- 1
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.91
Funders
- Science and Technology Commission of Shanghai Municipality
- Shanghai Municipal Population and Family Planning Commission