Research Participant Interest in Learning Results of Biomarker Tests for Alzheimer Disease
In this study of participants enrolled in a longitudinal aging study offered their research results, those with a parental history of AD dementia and Black participants were significantly more likely to decline. Qualitative interviews suggest that a family history of AD may create negative experiences and perceptions of the disease, which may influence the decision to learn results. Further research is needed to better understand racial differences in uptake and ensure that the choice to receive research results reflects individual preferences and wishes.
Authors
- Spondita Goswami (ORCID: https://orcid.org/0000-0002-3359-1869)
- Jessica Mozersky (ORCID: https://orcid.org/0000-0002-4942-4571)
- Sarah M. Hartz (ORCID: https://orcid.org/0000-0002-5429-3799)
- Erin Linnenbringer (ORCID: https://orcid.org/0000-0002-3883-0013)
- John C. Morris (ORCID: https://orcid.org/0000-0001-9820-5618)
- Krista L. Moulder
- Amy Oliver (ORCID: https://orcid.org/0000-0002-2507-6402)
- Sacha Jackson
- Alissa Evans
- Tomi Ogungbenle
Institutions
- Washington University in St. Louis (US)
- Saint Louis University (US)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.2919
- Citations
- 4
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 5.88