Spatial transcriptomic characteristics of gastric cancer in young and the expression and role of TMEM176B in gastric cancer cells
This study used ST-seq to map the transcriptomic profiles of the TCR, CAT, and NGT in patients with GCY, investigating gene spatial expression patterns and tumor heterogeneity. We identified TMEM176B's role in GC development and progression, offering molecular targets and a foundation for future treatments.
Authors
- Zhenhua Jiang (ORCID: https://orcid.org/0009-0003-9439-8709)
- Yong-Feng Wang (ORCID: https://orcid.org/0000-0003-0087-6507)
- Shuangyin Han (ORCID: https://orcid.org/0000-0003-3524-4796)
- Chi Zhang (ORCID: https://orcid.org/0000-0002-4593-7783)
Institutions
- Zhengzhou University (CN)
- The Fifth People's Hospital of Anyang (CN)
- Shandong Provincial Hospital (CN)
- Henan Provincial People's Hospital (CN)
- Zhengzhou People's Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1186/s40001-025-02577-5
- Citations
- 2
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 1.87