SLC7A11-HSPB1 axis: A novel mechanism for hepatocellular carcinoma progression and ferroptosis regulation
SLC7A11 plays a significant role in HCC progression by inhibiting ferroptosis, and its interaction with HSPB1 is a critical pathway in this process. Targeting the SLC7A11-HSPB1 axis may provide a novel therapeutic strategy for HCC treatment, highlighting the importance of understanding the mechanisms of ferroptosis in cancer cells.
Authors
- Weilong Liu (ORCID: https://orcid.org/0000-0001-7597-3200)
- Yuliang Deng (ORCID: https://orcid.org/0009-0001-0119-0016)
- Wanqiu Huang (ORCID: https://orcid.org/0000-0003-3354-1148)
- Jian Huang (ORCID: https://orcid.org/0000-0002-3153-0296)
- Yan An (ORCID: https://orcid.org/0009-0004-7089-2523)
Institutions
- Shanghai Jiao Tong University (CN)
- Southern University of Science and Technology (CN)
- Tongren Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
Publication Details
- Journal
- Biomedical Journal
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1016/j.bj.2025.100869
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56