Association of phenotypic aging, lifestyle, and genetic risk with incidence of atrial fibrillation: A large prospective cohort study in the UK Biobank
Increased PhenoAgeAccel is significantly associated with increased risk of AF. When combined with a poor lifestyle or high genetic risk, the risk is further increased. These findings highlight the importance of integrating phenotypic aging, genetic risk, and lifestyle factors into AF prevention strategies.
Authors
- Hao Lu (ORCID: https://orcid.org/0000-0002-0322-4400)
- Liangtang Zeng
- Qiang Li (ORCID: https://orcid.org/0000-0002-9815-4432)
- Ximin Fan (ORCID: https://orcid.org/0000-0003-1154-6861)
- Feilong Wang (ORCID: https://orcid.org/0000-0003-4607-3574)
- Tzeng‐Jih Lin
Institutions
- Tongji University (CN)
- Fudan University (CN)
- Zhongshan Hospital (CN)
- Shanghai Pulmonary Hospital (CN)
- Shanghai East Hospital (CN)
Publication Details
- Journal
- The journal of nutrition health & aging
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1016/j.jnha.2025.100562
- Citations
- 4
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 7.27