Sex hormone-binding globulin as a biomarker for metabolic risk in European women with polycystic ovary syndrome
SHBG levels <40 nmol/L are indicative for metabolic dysregulation in European women with PCOS. Waist circumference is an important predictor for SHBG, comparable to BMI. Visceral adiposity might play an important role in the expression of SHBG and etiology of PCOS.
Authors
- Olivier Valkenburg
- Bo E. van Bree (ORCID: https://orcid.org/0000-0002-2898-9178)
- Martijn C.G.J. Brouwers (ORCID: https://orcid.org/0000-0002-8229-3331)
- Marc E. A. Spaanderman
- Ron J T van Golde
- Denise M. B. van der Heijden
Institutions
- Radboud University Nijmegen (NL)
- Maastricht University Medical Centre (NL)
- Radboud University Medical Center (NL)
- Cardiovascular Institute Hospital (JP)
- Maastricht University (NL)
- Robert Bosch (India) (IN)
Publication Details
- Journal
- Gynecological Endocrinology
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1080/09513590.2025.2500462
- Citations
- 4
- Primary Topic
- Ovarian function and disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.79