Correlation Between Serum Iron with Platelet Count in Patients with End Stage Renal Disease (Esrd) on Hemodialysis at Gunung Jati Cirebon Hospital

Chronic Kidney Disease (CKD) is a kidney disorder that occurs gradually and irreversibly, characterized by structural abnormalities or abnormalities in kidney function lasts more than 3 months. CKD stage 5 (also known as ESRD) requires hemodialysis. ESRD on hemodialysis patients are often have iron deficiency. Serum iron levels may reflect changes in platelet counts, but correlation between them is still unclear. To determine the correlation between serum iron with platelet count in patients with ESRD on hemodialysis at Gunung Jati Cirebon Hospital. This is an observational research with a cross-sectional design and retrospective approach. Medical records containing serum iron level and platelet count from January to July 2024 were studied, with a maximum interval of 10 days between each test. Total of 55 samples were obtained. The data were analized using spearman's rho test. In this research, there were 37 (67,72%) patients were iron deficiency and 18 (32,73%) with a normal iron serum. The research also shown that 3 (5,45%) patients had thrombocytopenia, 47 (85,45%) patients had normal platelet count, and 5 (9,10%) had thrombocytosis. Spearman’s rho analysis were done resulting a p-value of 0,045 (p<0,05) and rho -0,271 (0,20-0,39). There was a significant correlation with negative affiliation between serum iron and platelet count in ESRD on hemodialysis patients at Gunung Jati Cirebon Hospital. The implication of this research is that low serum iron levels in ESRD patients undergoing hemodialysis can contribute to changes in platelet count, with a significant negative correlation.