A Novel Catheter-Based Method for Denervation of Afferent Renal Nerves in Sheep
This study establishes the feasibility of performing catheter-based afferent renal denervation in a large animal model. Furthermore, this study provides a translational model to evaluate catheter-based ARDN as a potential treatment for hypertension.
Authors
- Arthur Lynch (ORCID: https://orcid.org/0000-0001-7222-1329)
- Alex Dayton
- John P. Carney (ORCID: https://orcid.org/0000-0002-2090-7764)
- Dusty Van Helden (ORCID: https://orcid.org/0000-0001-5590-1496)
- Louise Evans (ORCID: https://orcid.org/0000-0002-7007-3825)
- Roman Tyshynsky (ORCID: https://orcid.org/0000-0003-2195-7875)
- Matthew T. Lahti (ORCID: https://orcid.org/0009-0007-0158-0560)
- Brianna Dailey-Krempel (ORCID: https://orcid.org/0000-0002-9217-5996)
- Lucy Vulchanova (ORCID: https://orcid.org/0000-0002-6577-4467)
- John W. Osborn (ORCID: https://orcid.org/0000-0002-8109-1578)
- D.T. Nguyen (ORCID: https://orcid.org/0000-0001-9849-9919)
Institutions
- University of Minnesota (US)
- University of Minnesota Medical Center (US)
Publication Details
- Journal
- Cardiovascular Engineering and Technology
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1007/s13239-025-00786-x
- Citations
- 1
- Primary Topic
- Blood Pressure and Hypertension Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Heart, Lung, and Blood Institute
- National Institute of Diabetes and Digestive and Kidney Diseases