A Common Medication With a Rare Side Effect: A Case Report of Statin-Induced Necrotizing Autoimmune Myopathy
Statins are commonly used for their cholesterol-lowering properties and are prescribed for primary and secondary prevention of cardiovascular disease. Although they are generally well tolerated, some individuals may experience a rare and serious side effect in which autoantibodies develop and lead to a necrotizing myopathy. Here we present a case of a middle-aged woman chronically on atorvastatin for her hyperlipidemia who acutely developed myalgias, muscle weakness, and persistently elevated creatine kinase, who was eventually diagnosed with statin-induced necrotizing autoimmune myopathy.
Authors
- Meghan Grossmann
- Michelle Jin (ORCID: https://orcid.org/0000-0002-8696-1958)
- Eric Scher
- Madison Drallmeier
Institutions
- Henry Ford Health System (US)
- Detroit Medical Center (US)
Publication Details
- Journal
- Cureus
- Published
- 2025-05-06
- DOI
- https://doi.org/10.7759/cureus.83589
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00