INNOVATIVE FEED MIXTURES FOR ANIMAL HEALTH PROTECTION

To combat dangerous infectious diseases in animals, antibiotics and vaccines are widely used. However, antibiotics can cause resistance in microorganisms and the transfer of antibiotic resistance genes from animals to humans, while vaccines do not always provide long-lasting immunity and are often ineffective against new strains of infectious disease pathogens. The feed mixture LAURIT 90, containing the active substance alpha-monolaurin, is used in animal husbandry as a strong natural antibacterial and antiviral agent. The antibacterial action of alpha-monolaurin is aimed at destroying the cell wall membranes of Gram-positive and Gram-negative pathogenic bacteria, leading to the death of microorganisms. Additionally, alpha-monolaurin is an effective agent in inhibiting the development of biofilms, characterized by a reduction in the number of viable bacteria associated with the biofilm, without affecting the beneficial gut microflora. The antiviral activity of alpha-monolaurin is aimed at destroying the lipoprotein coat of viruses, preventing their adsorption to the host cell plasma membrane, thus preventing infection and replication of the viruses. A significant advantage of the LAURIT 90 feed mixture is that it does not harm the organism’s microflora while effectively combating viruses and bacteria. The feed mixture is intended for use with various animal species for the prevention and treatment of bacterial and viral infections (poultry, pigs, calves, lambs, dogs, cats). The virucidal action of the feed mixture has been determined by the express method, which showed no lysis zones at the site of application of the mixture with bacteriophage. When testing the virucidal activity on live chicken embryo test systems (CET), the feed mixture showed pronounced virucidal activity against the Newcastle disease virus (NDV). The mortality of CET from NDV was 16 %. When testing the antimicrobial action of Laurit 90, the inhibition zones around discs with S. aureus-209 and E. coli were 22 mm and 23 mm, respectively.

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Publication Details

Journal
Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology
Published
2025-05-06
DOI
https://doi.org/10.36359/scivp.2025-26-1.26
Primary Topic
Animal Nutrition and Physiology
Type
article
Field-Weighted Citation Impact
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article

INNOVATIVE FEED MIXTURES FOR ANIMAL HEALTH PROTECTION

O. I. Chaykovska, V. V. Stybel, I. K. Avdos'eva, O. S. Kalinina et al.
Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology
Animal Nutrition and Physiology
article

INNOVATIVE FEED MIXTURES FOR ANIMAL HEALTH PROTECTION

O. I. Chaykovska, V. V. Stybel, I. K. Avdos'eva, O. S. Kalinina, S. M. Temnenko
article en

Abstract

To combat dangerous infectious diseases in animals, antibiotics and vaccines are widely used. However, antibiotics can cause resistance in microorganisms and the transfer of antibiotic resistance genes from animals to humans, while vaccines do not always provide long-lasting immunity and are often ineffective against new strains of infectious disease pathogens. The feed mixture LAURIT 90, containing the active substance alpha-monolaurin, is used in animal husbandry as a strong natural antibacterial and antiviral agent. The antibacterial action of alpha-monolaurin is aimed at destroying the cell wall membranes of Gram-positive and Gram-negative pathogenic bacteria, leading to the death of microorganisms. Additionally, alpha-monolaurin is an effective agent in inhibiting the development of biofilms, characterized by a reduction in the number of viable bacteria associated with the biofilm, without affecting the beneficial gut microflora. The antiviral activity of alpha-monolaurin is aimed at destroying the lipoprotein coat of viruses, preventing their adsorption to the host cell plasma membrane, thus preventing infection and replication of the viruses. A significant advantage of the LAURIT 90 feed mixture is that it does not harm the organism’s microflora while effectively combating viruses and bacteria. The feed mixture is intended for use with various animal species for the prevention and treatment of bacterial and viral infections (poultry, pigs, calves, lambs, dogs, cats). The virucidal action of the feed mixture has been determined by the express method, which showed no lysis zones at the site of application of the mixture with bacteriophage. When testing the virucidal activity on live chicken embryo test systems (CET), the feed mixture showed pronounced virucidal activity against the Newcastle disease virus (NDV). The mortality of CET from NDV was 16 %. When testing the antimicrobial action of Laurit 90, the inhibition zones around discs with S. aureus-209 and E. coli were 22 mm and 23 mm, respectively.

Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal BiologyVol. 26(1)
Stepan Gzhytskyi National University of Veterinary Medicine and Biotechnologies Lviv (UA), SCIVP of Veterinary Medicinal Products and Feed Additives (UA)
Openalex Percentile: Top 90%
Animal Nutrition and Physiology
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