Gene frequency and distribution of human platelet antigen-1 to −6, −10, −15, and −21 of platelets donors in Wuhan, China
Distinct gene frequencies and genotypes were observed for HPA-1 to -6, -10, -15, and -21 among 1516 platelet donors from Wuhan compared with those of other regions. These results highlight the fact that HPA genotyping is of great significance for the establishment of HPA genotype registry and precise platelet transfusion in Wuhan.
Authors
- Wangxia Li (ORCID: https://orcid.org/0000-0001-6927-1341)
- Xue Zheng (ORCID: https://orcid.org/0000-0003-4119-2945)
- Gang Shen (ORCID: https://orcid.org/0000-0001-5866-2099)
- Anyu Bao (ORCID: https://orcid.org/0000-0002-4098-8514)
- Mingdi He
- Zhen Qu
- Yuanyan Zhu
Institutions
- Wuhan University (CN)
- Renmin Hospital of Wuhan University (CN)
- Wuhan Blood Center (CN)
Publication Details
- Journal
- Global Medical Genetics
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1016/j.gmg.2025.100055
- Primary Topic
- Platelet Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00