Fluid-structure interaction analysis of bioinspired polymeric heart valves with experimental validation
This work demonstrates the potential of FSI simulations in predicting the hydrodynamic and mechanical behavior of PHVs, offering valuable insights into valve durability and design optimization for improved patient outcomes. This approach can significantly accelerate valve development by reducing reliance on extensive in vitro and in vivo testing.
Authors
- David S. Winlaw (ORCID: https://orcid.org/0000-0001-8005-3361)
- David F. Fletcher (ORCID: https://orcid.org/0000-0003-2221-4192)
- Nils Karajan
- Aeryne Lee (ORCID: https://orcid.org/0000-0002-2379-4531)
- Sina Naficy (ORCID: https://orcid.org/0000-0001-9168-6746)
- Karinna Shay Yee
- Luke Mosse
- Xinying Liu (ORCID: https://orcid.org/0000-0001-8891-0778)
- Thanh Phuong Hoang (ORCID: https://orcid.org/0009-0003-6729-711X)
- Yiqi Wang
Institutions
- Northwestern University (US)
- The University of Sydney (AU)
- Ansys (United States) (US)
- Lurie Children's Hospital (US)
- Robert H. Lurie Comprehensive Cancer Center of Northwestern University
Publication Details
- Journal
- Computer Methods and Programs in Biomedicine
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1016/j.cmpb.2025.108839
- Citations
- 1
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.39