Acute Legionnaires’ Disease–Associated Complete Heart Block

Legionnaires’ disease is a systemic disease caused by Legionella species that predominantly affects the lungs; however, extrapulmonary manifestations including cardiac involvement have been reported. We present a case of a 79-year-old woman who presented with cough, reduced appetite, and syncope and was found to be in third-degree atrioventricular block. The patient had a positive urine Legionella antigen with a finding on computed tomography of the chest of bilateral infiltrates. Despite antibiotic therapy, permanent pacemaker was implanted for persistent complete heart block. At 2-week follow-up, however, patient had regained intrinsic conduction. This case highlights Legionnaires’ disease as a potential reversible cause of complete heart block.

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Publication Details

Journal
Annals of Internal Medicine Clinical Cases
Published
2025-05-01
DOI
https://doi.org/10.7326/aimcc.2024.1243
Primary Topic
Legionella and Acanthamoeba research
Type
article
Field-Weighted Citation Impact
0.00
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article

Acute Legionnaires’ Disease–Associated Complete Heart Block

Iriagbonse Asemota, A Montano, Humayun Naqvi, Nilesh Mathuria et al.
Annals of Internal Medicine Clinical Cases
Legionella and Acanthamoeba research
article

Acute Legionnaires’ Disease–Associated Complete Heart Block

Iriagbonse Asemota, A Montano, Humayun Naqvi, Nilesh Mathuria, Janice Koshy
article en

Abstract

Legionnaires’ disease is a systemic disease caused by Legionella species that predominantly affects the lungs; however, extrapulmonary manifestations including cardiac involvement have been reported. We present a case of a 79-year-old woman who presented with cough, reduced appetite, and syncope and was found to be in third-degree atrioventricular block. The patient had a positive urine Legionella antigen with a finding on computed tomography of the chest of bilateral infiltrates. Despite antibiotic therapy, permanent pacemaker was implanted for persistent complete heart block. At 2-week follow-up, however, patient had regained intrinsic conduction. This case highlights Legionnaires’ disease as a potential reversible cause of complete heart block.

Annals of Internal Medicine Clinical CasesVol. 4(5)
Methodist Hospital (US), University of Houston (US)
Openalex Percentile: Top 92%
Legionella and Acanthamoeba research
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