An Unusual Cause of Gastrointestinal Bleeding

This case report discusses a rare cause of gastrointestinal bleeding in an older man with several comorbidities. The colonoscopy revealed a fragile, vegetative mass in the cecum with an abnormal vessel architecture. The histopathologic examination and the immunohistochemical staining of the resected tumor yielded a diagnosis of high-grade angiosarcoma. During the initial work-up for gastrointestinal bleeding, another primary cancer located at the pancreatic tail was discovered incidentally, the latter being an adenocarcinoma. The patient had right hemicolectomy, distal pancreatectomy, and splenectomy. The association of this rare colonic angiosarcoma with another primary tumor and associated comorbidities are discussed.