To Switch or not to Switch to Long-acting Injectable Cabotegravir/Rilpivirine in PWH With Past Hepatitis B Virus (HBV) Coinfection: Which HBV Markers to Manage Risk of HBV Reactivation?

We report the occurrence of low-level hepatitis B virus (HBV) viremia in people with HIV with controlled CD4 counts and isolated core antibody reactivity switched to long-acting injectable cabotegravir/rilpivirine. This series raises questions about the reintroduction of anti-HBV medications, presents the variation of several HBV markers alongside HBV-DNA and reveals an effective spontaneous immune response.

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Publication Details

Journal
Open Forum Infectious Diseases
Published
2025-05-06
DOI
https://doi.org/10.1093/ofid/ofaf266
Citations
4
Primary Topic
Hepatitis B Virus Studies
Type
article
Field-Weighted Citation Impact
5.42
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article

To Switch or not to Switch to Long-acting Injectable Cabotegravir/Rilpivirine in PWH With Past Hepatitis B Virus (HBV) Coinfection: Which HBV Markers to Manage Risk of HBV Reactivation?

Vincent Thibault, David Chirio, Laurence Ollier, Pascal Puglièse et al.
4 citations
Open Forum Infectious Diseases
Hepatitis B Virus Studies
5.42
article

To Switch or not to Switch to Long-acting Injectable Cabotegravir/Rilpivirine in PWH With Past Hepatitis B Virus (HBV) Coinfection: Which HBV Markers to Manage Risk of HBV Reactivation?

Vincent Thibault, David Chirio, Laurence Ollier, Pascal Puglièse, Alissa Naqvi, Michel Carles, Anne De Monte, J. Durant
article en
4 citations

Abstract

We report the occurrence of low-level hepatitis B virus (HBV) viremia in people with HIV with controlled CD4 counts and isolated core antibody reactivity switched to long-acting injectable cabotegravir/rilpivirine. This series raises questions about the reintroduction of anti-HBV medications, presents the variation of several HBV markers alongside HBV-DNA and reveals an effective spontaneous immune response.

Open Forum Infectious DiseasesVol. 12(6)
3M (United States) (US), Inserm (FR), Université Côte d'Azur (FR), Centre Hospitalier Universitaire de Nice (FR), Centre Hospitalier Universitaire de Rennes (FR)
Openalex Percentile: Top 4%
Hepatitis B Virus Studies
5.42
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