Factors Influencing Severe Hematologic Toxicity Following Niraparib Therapy in Patients With Ovarian Cancer

Creatinine clearance is a risk factor for severe hematologic toxicity. A creatinine clearance value <47.0 ml/min may slightly increase the risk of this toxicity in patients with ovarian cancer receiving niraparib.

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Publication Details

Journal
Cancer Diagnosis & Prognosis
Published
2025-05-03
DOI
https://doi.org/10.21873/cdp.10450
Primary Topic
PARP inhibition in cancer therapy
Type
article
Field-Weighted Citation Impact
0.00
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article

Factors Influencing Severe Hematologic Toxicity Following Niraparib Therapy in Patients With Ovarian Cancer

Shiori Yamada, Michio Kimura, Rina Matsuyama, Makiko Go et al.
Cancer Diagnosis & Prognosis
PARP inhibition in cancer therapy
article

Factors Influencing Severe Hematologic Toxicity Following Niraparib Therapy in Patients With Ovarian Cancer

Shiori Yamada, Michio Kimura, Rina Matsuyama, Makiko Go, Eiseki Usami
article en

Abstract

Creatinine clearance is a risk factor for severe hematologic toxicity. A creatinine clearance value <47.0 ml/min may slightly increase the risk of this toxicity in patients with ovarian cancer receiving niraparib.

Cancer Diagnosis & PrognosisVol. 5(3)
Ogaki Municipal Hospital (JP)
Good health and well-being
Openalex Percentile: Top 85%
PARP inhibition in cancer therapy
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