Facial Diffuse Plexiform Neurofibroma‐associated Mandibular Deformities: Surgical Interventions and Monitoring of Treatment Results in a Patient for Over 40 Years

Head and neck diffuse plexiform neurofibroma can be associated with craniofacial bone malformations. Distinction between deformity-related bone changes from an infiltrating and destructive tumor can be difficult, especially in cases of rapidly progressive local bone loss. Presumably, both tumor-associated functional lesions of the masticatory muscles and tumor-related effects on the bone influence the shape of the affected bone. Diagnosis of tumor-associated bone lesions can be challenging in NF1. Reconstructive bone surgery of the jaw provides options for functional and esthetic improvement of the affected individual. However, long-term follow-up checks are advisable to assess treatment results. An exact assessment of the tumor type and long-term monitoring of the findings are the basis of a viable surgical therapy.