Perspective on an Innovative Curative Strategy for Peritoneal Metastasis Involving Peritonectomy, Hyperthermic Intraperitoneal Chemotherapy, and Adjuvant Chemotherapy Identified as Effective in the Histoculture Drug Response Assay (HDRA)
The present innovative treatment of PACC with peritoneal metastases used laparotomy to determine the extent of peritoneal metastases, peritonectomy to attempt to completely remove the tumor, HIPEC for intraoperative hyperthermic-chemotherapy, and the HDRA to determine the most effective drug for adjuvant chemotherapy. These procedures can be individualized for each patient's cancer, and the HDRA is most critical for individualization.
Authors
- Hiroaki Kimura (ORCID: https://orcid.org/0000-0002-7441-0382)
- Hiroyuki Tsuchiya
- Byung Mo Kang (ORCID: https://orcid.org/0000-0003-0900-094X)
- Takashi Higuchi (ORCID: https://orcid.org/0000-0002-7489-1657)
- Yohei Asano (ORCID: https://orcid.org/0000-0002-8777-6076)
- Robert M. Hoffman (ORCID: https://orcid.org/0000-0002-0049-0041)
- Yutaka Yonemura (ORCID: https://orcid.org/0000-0002-2458-4106)
- Shinji Miwa
- KOHEI MIZUTA
- Satoru Demura
- Norio Yamamoto (ORCID: https://orcid.org/0000-0001-8924-0710)
- CHIHIRO HOZUMI
- Kentaro Igarashi (ORCID: https://orcid.org/0000-0003-2278-1736)
- Sei Morinaga (ORCID: https://orcid.org/0000-0003-2961-9432)
- Jin-Soo Kim (ORCID: https://orcid.org/0000-0002-1847-3741)
- Katsuhiro Hayashi
Institutions
- Kanazawa University (JP)
- University of California San Diego (US)
- AntiCancer (United States) (US)
Publication Details
- Journal
- Cancer Diagnosis & Prognosis
- Published
- 2025-05-03
- DOI
- https://doi.org/10.21873/cdp.10440
- Citations
- 1
- Primary Topic
- Intraperitoneal and Appendiceal Malignancies
- Type
- article
- Field-Weighted Citation Impact
- 2.01