Development and Validation of Mortality Prediction Models among Frail Participants in the UK Biobank Study

Survey-based models predicted mortality in frail individuals effectively, with only minor improvements from adding biomarkers or physical measurements. These findings highlighted the value of surveys in forecasting outcomes and informed personalized management strategies to improve health for the frail.

Authors

Qian‐Li Xue (ORCID: https://orcid.org/0000-0001-8818-7444)
Chenkai Wu (ORCID: https://orcid.org/0000-0002-2256-0653)
Junhan Tang
Jonathan K. L. Mak (ORCID: https://orcid.org/0000-0003-4454-8580)
Yanxin Wang (ORCID: https://orcid.org/0000-0002-4098-138X)
Jianhong Xu

Institutions

Johns Hopkins University (US)
Chinese University of Hong Kong (HK)
Johns Hopkins Medicine (US)
Karolinska Institutet (SE)
Duke Kunshan University (CN)
University of Hong Kong (HK)

Publication Details

Journal: The Journals of Gerontology Series A
Published: 2025-05-02
DOI: https://doi.org/10.1093/gerona/glaf096
Primary Topic: Frailty in Older Adults
Type: article
Field-Weighted Citation Impact: 0.00

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article

Development and Validation of Mortality Prediction Models among Frail Participants in the UK Biobank Study

Qian‐Li Xue, Chenkai Wu, Junhan Tang, Jonathan K. L. Mak et al.

May 2, 2025

The Journals of Gerontology Series A

Frailty in Older Adults

article

Development and Validation of Mortality Prediction Models among Frail Participants in the UK Biobank Study

Qian‐Li Xue, Chenkai Wu, Junhan Tang, Jonathan K. L. Mak, Yanxin Wang, Jianhong Xu

May 2, 2025article en

Abstract

Survey-based models predicted mortality in frail individuals effectively, with only minor improvements from adding biomarkers or physical measurements. These findings highlighted the value of surveys in forecasting outcomes and informed personalized management strategies to improve health for the frail.

The Journals of Gerontology Series AVol. 80(7)

Johns Hopkins University (US), Chinese University of Hong Kong (HK), Johns Hopkins Medicine (US), Karolinska Institutet (SE), Duke Kunshan University (CN), University of Hong Kong (HK)

Openalex Percentile: Top 89%

Frailty in Older Adults

DOI Source OpenAlex

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Development and Validation of Mortality Prediction Models among Frail Participants in the UK Biobank Study — Qian‐Li Xue, Chenkai Wu, et al. · The Journals of Gerontology Series A (2025) | TGRS Research Map | TGRS