The Relationship between Systemic Expression Levels of Immune Cells and Tumor Markers and High-Risk HPV Infection in Patients with Cervical Cancer, Cervical Intraepithelial Neoplasia, and Chronic Cervicitis, and its Clinical Significance
Compared with patients with CIN and chronic cervicitis associated with high-risk HPV infection, cervical cancer patients exhibit decreased systemic immune function and increased circulating tumor marker expression. These findings are closely associated with HPV-DNA levels. Systemic detection of these markers may provide valuable guidance for the early prevention, diagnosis, and prognosis assessment of cervical cancer in patients with high-risk HPV infection.
Authors
- Shujuan Shao (ORCID: https://orcid.org/0000-0002-1138-9889)
- L L Wang
- Suning Chen (ORCID: https://orcid.org/0000-0001-6294-972X)
- Hongli Wang (ORCID: https://orcid.org/0000-0003-0655-3389)
- Yajuan Wang
- Huiying Wang (ORCID: https://orcid.org/0000-0003-0639-7507)
- Hongxia Li
- Pengfei Guo (ORCID: https://orcid.org/0000-0002-7662-9070)
- Lirui Wu
Institutions
- Hospital of Hebei Province (CN)
- China People's Police University (CN)
Publication Details
- Journal
- International Journal of Women s Health
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2147/ijwh.s515393
- Citations
- 1
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 1.35