Loop and thiazide diuretics and outcomes in heart failure with preserved ejection fraction
In HFpEF, baseline use and higher doses of loop diuretics were associated with higher risk of CV death and total HHFs. Thiazide alone was not associated with any endpoints, but when added to loop diuretics it was associated with additional risk for all outcomes.
Authors
- Gianluigi Savarese (ORCID: https://orcid.org/0000-0001-7732-0887)
- Lina Benson
- Federica Guidetti (ORCID: https://orcid.org/0009-0005-1659-7731)
- Lars H. Lund (ORCID: https://orcid.org/0000-0003-1411-4482)
- Tonje Thorvaldsen
- Camilla Hage (ORCID: https://orcid.org/0000-0002-4142-2416)
- Bertram Pitt
- Barna Szabó‐Söderberg
Institutions
- Karolinska University Hospital (SE)
- University of Michigan (US)
- Karolinska Institutet (SE)
- Stockholm South General Hospital (SE)
Publication Details
- Journal
- American Heart Journal
- Published
- 2025-05-06
- DOI
- https://doi.org/10.1016/j.ahj.2025.04.029
- Citations
- 5
- Primary Topic
- Heart Failure Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 6.94
Funders
- Hjärt-Lungfonden
- Stockholms Läns Landsting
- Vetenskapsrådet
- Medicinska Forskningsrådet
- National Institutes of Health
- National Heart, Lung, and Blood Institute